Selected Publications

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Year Paper Title
2002 A. Hildesheim*, R. J. Apple, C. J. Chen, S. S. Wang, Y. C. Cheng, W. Klitz, S. J. Mack, I. H. Chen, M. M. Hsu, C. S. Yang, L. A. Brinton, P. H. Levine, H. A. Erlich, Association of HLA class I and II alleles and extended haplotypes with nasopharyngeal carcinoma in Taiwan, J Natl Cancer Inst, vol. 94, 1780-1789, 2002
2002 M. W. Yu*, Y. C. Yang, S. Y. Yang, H. C. Chang, Y. F. Liaw, S. M. Lin, C. J. Liu, S. D. Lee, C. L. Lin, P. J. Chen, S. C. Lin, C. J. Chen, Androgen receptor exon 1 CAG repeat length and risk of hepatocellular carcinoma in women, Hepatology, vol. 36, 156-163, 2002
2002 C. J. Chiu, W. C. Lee, C. P. Chiang, L. J. Hahn, Y. S. Kuo, C. J. Chen*, A scoring system for the early detection of oral submucous fibrosis based on a self-administered questionnaire, J Public Health Dent, vol. 62, 28-31, 2002
2001 B. Buhler, Y. C. Lin, G. Morris, A. J. Olson, D. D. Richman, J. H. Elder, B. E. Torbett, Viral evolution in response to the broad-based retroviral protease inhibitor TL-3, J Virol, vol. 75, 9502-9508, 2001
2001 P. Sears, Toward automated synthesis of oligosaccharides and glycoproteins, Science, vol. 291, 2344-2350, 2001
2001 C. S. Yu, K. Niikura, C. C. Lin, The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the alpha-Glycosylation of Primary Hydroxy Groups This research was supported by Academia Sinica (Taipei) and the NIH (USA), ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 2900-2903, 2001
2001 F. Burkhart, Z. Y. Zhang, S. Wacowich Sgarbi, Synthesis of the Globo H hexasaccharide using the programmable reactivity-based one-pot strategy ( This research was supported by the National Institutes of Health. F.B. thanks the Deutsche Forschungsgemeinschaft for a fellowship), ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 1274-1277, 2001
2001 I. A. Kozlov, S. Mao, Y. Xu, X. Huang, L. Lee, P. S. Sears, C. Gao, A. R. Coyle, K. D. Janda, Synthesis of solid-supported mirror-image sugars: a novel method for selecting receptors for cellular-surface carbohydrates, Chembiochem, vol. 2, 741-746, 2001
2001 T. K. Ritter, Synthesis of N-acetylglucosamine thiazoline/lipid II hybrids, Tetrahedron Lett, vol. 42, 615-618, 2001
2001 V. D. Le, C. C. Mak, Y. C. Lin, J. H. Elder, Structure-activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine, BIOORGANIC & MEDICINAL CHEMISTRY, vol. 9, 1185-1195, 2001
2001 Y. Ichikawa, G. J. Shen, Production of fucosylated carbohydrates by enzymatic fucosylation; synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose, US Patent, vol. #6,319,695, 2001
2001 M. G. Silvestri, Opening of thiiranes: preparation of orthogonal protected 2-thioglyceraldehyde, J Org Chem, vol. 66, 910-914, 2001
2001 A. Heine, G. DeSantis, J. G. Luz, M. Mitchell, I. A. Wilson, Observation of covalent intermediates in an enzyme mechanism at atomic resolution, Science, vol. 294, 369-374, 2001
2001 M. Izumi, Microbial sialyltransferases for carbohydrate synthesis, TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY, vol. 13, 345-360, 2001
2001 M. Izumi, G. J. Shen, S. Wacowich Sgarbi, T. Nakatani, O. Plettenburg, Microbial glycosyltransferases for carbohydrate synthesis: alpha-2,3-sialyltransferase from Neisseria gonorrheae, J Am Chem Soc, vol. 123, 10909-10918, 2001
2001 Inhibition of human fucosyltransferases with N-linked Lewis-x and LacNAc analogs, US Patent, vol. #6,232,450, 2001
2001 X. F. Huang, K. L. Witte, D. E. Bergbreiter, Homogenous enzymatic synthesis using a thermo-responsive water-soluble polymer support, Adv Synth Catal, vol. 343, 675-681, 2001
2001 J. Liu, A. R. Shikhman, M. K. Lotz, Hexosaminidase inhibitors as new drug candidates for the therapy of osteoarthritis, Chem Biol, vol. 8, 701-711, 2001
2001 K. M. Koeller, Enzymes for chemical synthesis, Nature, vol. 409, 232-240, 2001
2001 M. D. Burkart, Enzymatic sulfation of biomolecules, US Patent, vol. # 6,255,088, 2001
2001 Editorial commentary, Adv Synth Catal, vol. 343, 495-495, 2001
2001 C. C. Mak, V. D. Le, Y. C. Lin, J. H. Elder, Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue, Bioorg Med Chem Lett, vol. 11, 219-222, 2001
2001 X. S. Ye, X. F. Huang, Conversion of the carboxy group of sialic acid donors to a protected hydroxymethyl group yields an efficient reagent for the synthesis of the unnatural beta-linkage, Chem Commun, vol. 11, 974-975, 2001
2001 C. Saotome, O. Kanie, Combinatorial library of five-membered iminocyclitol and the inhibitory activities against glyco-enzymes, Chem Biol, vol. 8, 1061-1070, 2001
2001 M. Mitchell, L. Qaio, Chemical-enzymatic synthesis of iminocyclitol phosphonic acids, Adv Synth Catal, vol. 343, 596-599, 2001
2001 T. K. Ritter, Carbohydrate-Based Antibiotics: A New Approach to Tackling the Problem of Resistance, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 40, 3508-3533, 2001
2001 H. Liu, R. Sadamoto, P. S. Sears, An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides, J Am Chem Soc, vol. 123, 9916-9917, 2001
2001 Y.C. Lee, S.D. Lin, H.M. Yu, S.T. Chen, Phosphorylation of the 24p3 protein secreted from mouse uterus in vitro and in vivo, JOURNAL OF PROTEIN CHEMISTRY, vol. 20, 563-569, 2001
2001 C.L.Ho, Y.P.Shih, K.T.Wang, H.M.Yu, Enhancing the hypotensive effect and diminishing the cytolytic activity of hornet mastoparan B by D-amino acid substitution, TOXICON, vol. 39, 1561-1566, 2001
2001 W. B. Yang, C.Y. Wu, C. C. Chang, S. H. Wang, C. F. Teo, C. H. Lin, Facile synthesis of conjugated exo-glycals, Tetrahedron Lett, vol. 42, 6907-6910, 2001