具代表性研究發表

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年度 論文名稱
1987 D. C. Chung*, Y. C. Ko, C. J. Chen, C. C. Wu, Z. H. Wang, Epidemiological study on hepatitis B virus infection among five ethnic groups in Pingtung County, Taiwan, J Formos Med Assoc, vol. 86, 497-504, 1987
1987 C. J. Chen*, T. M. Lin, C. Chang, Y. J. Cheng, Epidemiological characteristics of twinning rates in Taiwan, Acta Genet Med Gemellol, vol. 36, 335-342, 1987
1987 J. Y. Chen, C. J. Chen, M. Y. Liu, S. M. Cho, M. M. Hsu, T. C. Lynn, T. Shieh, S. M. Tu, H. H. Lee, S. L. Kuo, M. Y. Lai, C. Y. Hsieh, C. P. Hu, C. S. Yang*, Antibodies to Epstein-Barr virus-specific DNAse in patients with nasopharyngeal carcinoma and control groups, J Med Virol, vol. 23, 11-21, 1987
1987 Chen CJ, Cheng SH, Lee SS, Wu HY, Analysis of cancer mortality rates of 789 blackfoot disease patients, Blackfoot Disease Research Report, vol. 26:21-37, 1987
1987 Chen CJ, Lee SS, Cheng SH, Wu HY, Wang JD, A case-control study on multifactorial etiology of blackfoot disease: A preliminary report, Blackfoot Disease Research Report, vol. 26:1-20, 1987
1986 Nicotinamide cofactor-requiring enzymatic synthesis in organic solvent-water biphasic systems, Biocatalysis in Organic Media, vol. 197-208, 1986
1986 Enzyme-catalyzed synthesis of unusual carbohydrates and peptides, Proceeding of 5th International Symposium on Life Science: Prospects for Enzyme Technology, vol. 86-89, 1986
1986 J. B. West, Enzyme-Catalyzed Synthesis of Peptides Containing D-Amino Acids, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, vol. 417-418, 1986
1986 H. M. Sweers, Enzyme-Catalyzed Regioselective Deacylation of Protected Sugars in Carbohydrate Synthesis, J Am Chem Soc, vol. 108, 6421-6422, 1986
1986 J. B. West, Enzyme-Catalyzed Irreversible Formation of Peptides Containing D-Amino Acids, J Org Chem, vol. 51, 2728-2735, 1986
1986 J. B. West, Enzymatic-Synthesis of Peptides Containing D-Amino Acids, FEDERATION PROCEEDINGS, vol. 45, 1789-1789, 1986
1986 J. R. Durrwachter, H. M. Sweers, K. Nozaki, Enzymatic aldol reaction/isomerization as a route to unusual sugars, Tetrahedron Lett, vol. 27, 1261-1264, 1986
1986 J. R. Durrwachter, D. G. Drueckhammer, K. Nozaki, H. M. Sweers, Enzymatic Aldol Condensation Isomerization as a Route to Unusual Sugar-Derivatives, J Am Chem Soc, vol. 108, 7812-7818, 1986
1986 S. T. Chen, K. T. Wang, Chirally Selective Hydrolysis of D,L-Amino Acid-Esters by Alkaline Protease, JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, vol. 1514-1516, 1986
1986 J. R. Matos, Biphasic One-Pot Synthesis of 2 Useful and Separable Compounds Using Cofactor-Requiring Enzymatic-Reactions - Glutamate-Dehydrogenase Catalyzed Synthesis of L-Alpha-Aminoadipate Coupled with Alcohol-Dehydrogenase Catalyzed Synthesis of a Chiral Lactone, J Org Chem, vol. 51, 2388-2389, 1986
1986 Aldolases as catalysts in organic synthesis, In: Enzymes as Catalysts in Organic Synthesis, vol. 199-216, 1986
1986 T. M. Lin*, H. J. Chang, C. J. Chen, Y. J. Cheng, C. S. Yang, S. M. Tu, Y. Ito, A. Jr. Kawamura, T. Hirayama, Risk factors for nasopharyngeal carcinoma, Anticancer Res, vol. 6, 791-796, 1986
1986 T. M. Lin*, W. J. Tsu, C. J. Chen, Mortality of hepatoma and cirrhosis of liver in Taiwan, Brit J Cancer, vol. 54, 969-976, 1986
1986 M. M. Wu, C. J. Chen*, C. H. Lee, Evaluation of the reporting system for communicable diseases in Taipei, 1981-1983, J Natl Public Health Assoc, vol. 6, 38-49, 1986
1986 C. J. Chen, Y. C. Chuang, S. L. You, T. M. Lin, H. Y. Wu, A retrospective study on malignant neoplasms of bladder, lung and liver in blackfoot disease endemic area in Taiwan, Br J Cancer, vol. 53, 399-405, 1986
1985 D. G. Drueckhammer, V. W. Riddle, Fmn Reductase Catalyzed Regeneration of Nad(P) for Use in Enzymatic-Synthesis, J Org Chem, vol. 50, 5387-5389, 1985
1985 Enzymes in organic synthesis: aldol condensation, Industrial Chemical News, vol. 6, 24-25, 1985
1985 G. M. Whitesides, Enzymes as Catalysts in Synthetic Organic Chemistry, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, vol. 24, 617-638, 1985
1985 R. L. Root, J. R. Durrwachter, Enzymatic-Synthesis of Unusual Sugars - Galactose-Oxidase Catalyzed Stereospecific Oxidation of Polyols, J Am Chem Soc, vol. 107, 2997-2999, 1985
1985 D. G. Drueckhammer, H. M. Sweers, Enzymatic Vs Fermentative Synthesis - Thermostable Glucose-Dehydrogenase Catalyzed Regeneration of Nad(P)H for Use in Enzymatic-Synthesis, J Am Chem Soc, vol. 107, 4028-4031, 1985
1985 D. G. Drueckhammer, Enzymatic synthesis of chiral hydroxy compounds using immobilized glucose dehydrogenase from Bacillus cereus for NAD(P)H regeneration, NATURE BIOTECHNOLOGY, vol. 3, 649-651, 1985
1985 J. R. Matos, M. B. Smith, Enantioselectivity of Alcohol Dehydrogenase-Catalyzed Oxidation of 1,2-Diols and Aminoalcohols, BIOORGANIC CHEMISTRY, vol. 13, 121-130, 1985
1985 J. R. Matos, Enantioselective Oxidation of 1,2-Diols to L-Alpha-Hydroxy Acids Using Coimmobilized Alcohol and Aldehyde Dehydrogenases as Catalysts, J Org Chem, vol. 50, 1992-1994, 1985
1985 D. G. Drueckhammer, Chemoenzymatic Syntheses of Fluoro Sugar Phosphates and Analogs, J Org Chem, vol. 50, 5912-5913, 1985
1985 Chen CJ, Wang LJ, Tay SC, Lim CB, Chang CC, Wang KF, Prevalence of poliomyelitis among Taipei City school children, Epidemiol Bull, vol. 1, 41-46, 1985
1985 C. J. Chen*, Y. C. Chuang, T. M. Lin, H. Y. Wu, Malignant neoplasms among residents of a blackfoot disease-endemic area in Taiwan: High-arsenic artesian well water and cancers, Cancer Res, vol. 45, 5895-5899, 1985
1985 C. J. Chen*, B. H. Cohen, E. L. Diamond, Genetic and environmental effects on the development of myopia in Chinese twin children, Ophthalmic Pediatr Genet, vol. 6, 353-359, 1985
1985 J. Y. Chen, M. Y. Liu, C. J. Chen, M. M. Hsu, S. M. Tu, H. H. Lee, S. L. Kuo, C. S. Yang*, Antibody to Epstein-Barr virus-specific DNase as a marker for the early detection of nasopharyngeal carcinoma, J Med Virol, vol. 17, 47-49, 1985
1984 G.M. Whitesides, P.F. Mazenod, Preparation of 6-Deoxy-d-Fructose and 6-deoxy-L-Sorbose, US Patent, vol. #4,440,854, 1984
1984 C. J. Chen*, B. H. Cohen, E. L. Diamond, T. M. Lin, J. S. Chen, Genetic variance and heritability of cardiovascular risk factors in Chinese adolescent twins, Acta Genet Med Gemellol, vol. 33, 363-373, 1984
1984 C. J. Chen*, T. M. Lin, S. L. You, Epidemiological aspects of a poliomyelitis outbreak in Taiwan, 1982, Ann Acad Med Singapore, vol. 13, 149-155, 1984
1984 C. J. Chen*, B. H. Cohen, E. L. Diamond, T. M. Lin, J. S. Chen, Environmental effects on cardiovascular risk factors in Chinese adolescent monozygotic twins, Acta Genet Med Gemellol, vol. 33, 375-381, 1984
1984 C. J. Chen*, B. H. Cohen, E. L. Diamond, T. M. Lin, J. S. Chen, Effects of gene-environment interactions on cardiovascular risk factors in Chinese adolescent twins, Acta Genet Med Gemellol, vol. 33, 383-396, 1984
1984 Chen CJ, Wu HY, Chuang YC, You SL, Sun KC, Lin TM, Cancer epidemiology in blackfoot disease-endemic areas, Blackfoot Disease Research Report, vol. 21:8-38, 1984
1984 C. J. Chen*, T. M. Lin, Y. L. Yeh, Analysis of the secular trend and seasonal variation of measles mortality rate in Taiwan, Ann Acad Med Singapore, vol. 13, 136-141, 1984
1984 C. Chang*, L. W. Yeh, Y. C. Li, C. J. Chen, A study on the applicability of Eysenck Personality Inventory Scale in elementary schools, Psychol Test, vol. 31, 91-102, 1984
1983 G. M. Whitesides, Synthesis of Sugars by Aldolase-Catalyzed Condensation-Reactions, J Org Chem, vol. 48, 3199-3205, 1983
1983 S. L. Haynie, G. M. Whitesides, Preparation of a Mixture of Nucleoside Triphosphates from Yeast Rna - Use in Enzymatic-Synthesis Requiring Nucleoside Triphosphate Regeneration and Conversion to Nucleoside Diphosphate Sugars, J Am Chem Soc, vol. 105, 115-117, 1983
1983 G. M. Whitesides, Enzymes as catalysts in organic synthesis, Aldrichimica Acta, vol. 16, 27-34, 1983
1983 G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Regeneration of Deuterated Nicotinamide Cofactors for Use in Large-Scale Enzymatic-Synthesis of Deuterated Substances, J Am Chem Soc, vol. 105, 5012-5014, 1983
1983 F. P. Mazenod, G. M. Whitesides, Chemical and Enzymatic Syntheses of 6-Deoxyhexoses - Conversion to 2,5-Dimethyl-4-Hydroxy-2,3-Dihydrofuran-3-One (Furaneol) and Analogs, J Org Chem, vol. 48, 3493-3497, 1983
1983 C. H. Chiang*, W. C. Chi, C. J. Chen, C. L. Yaung, A study of knowledge, attitude and practice of Shuhu residents on poliomyelitis vaccination, J Natl Public Health Assoc, vol. 2, 63-83, 1983
1982 A. Pollak, S. D. McCurry, J. M. Sue, J. R. Knowles, G. M. Whitesides, Synthesis of ribulose 1,5-bisphosphate: routes from glucose 6-phosphate (via 6-phosphogluconate) and from adenosine monophosphate (via ribose 5-phosphate), Methods Enzymol, vol. 89 Pt D, 108-121, 1982
1982 Enzymes as catalysts in organic synthesis, Ph.D. Dissertation, Massachusetts Institute of Technology, 1982
1982 G. M. Whitesides, Enzyme-Catalyzed Transhydrogenation between Nicotinamide Cofactors and Its Application in Organic-Synthesis, J Am Chem Soc, vol. 104, 3542-3544, 1982
1982 S. L. Haynie, G. M. Whitesides, Enzyme-Catalyzed Synthesis of N-Acetyllactosamine with Insitu Regeneration of Uridine 5'-Diphosphate Glucose and Uridine 5'-Diphosphate Galactose, J Org Chem, vol. 47, 5416-5418, 1982
1982 G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Nad(P)H Cofactor Regeneration Using Ethanol Alcohol-Dehydrogenase Aldehyde Dehydrogenase and Methanol Alcohol-Dehydrogenase Aldehyde Dehydrogenase Formate Dehydrogenase, J Org Chem, vol. 47, 2816-2818, 1982
1982 G. M. Whitesides, C. M. Wong, A. Pollak, Asymmetric synthesis using cofactor-requiring enzymes, Asymmetric Reactions and Processes in Chemistry, vol. 185, 205-218, 1982
1982 T. H. Beaty*, B. H. Cohen, C. A. Newill, H. A. Menkes, E. L. Diamond, C. J. Chen, Impaired pulmonary function as a risk factor for mortality, Am J Epidemiol, vol. 116, 102-113, 1982
1982 R. P. Beasley*, C. C. Lin, C. S. Chien, C. J. Chen, L. Y. Hwang, Geographic distribution of HBsAg carriers in China, Hepatology, vol. 2, 553-556, 1982
1981 J. Gordon, C. L. Cooney, G. M. Whitesides, Regeneration of Nad(P)H Using Glucose 6-Sulfate and Glucose-6-Phosphate-Dehydrogenase, J Org Chem, vol. 46, 4676-4679, 1981
1981 L. Daniels, W. H. Ormejohnson, G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Nad(P)H Regeneration Using Dihydrogen and the Hydrogenase from Methanobacterium-Thermoautotrophicum, J Am Chem Soc, vol. 103, 6227-6228, 1981
1981 G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Nad(P)H Cofactor Regeneration by Using Glucose-6-Phosphate and the Glucose-6-Phosphate-Dehydrogenase from Leuconostoc-Mesenteroides, J Am Chem Soc, vol. 103, 4890-4899, 1981
1981 R. Dicosimo, L. Daniels, G. M. Whitesides, Enzyme-Catalyzed Organic-Synthesis - Electrochemical Regeneration of Nad(P)H from Nad(P) Using Methyl Viologen and Flavoenzymes, J Org Chem, vol. 46, 4622-4623, 1981
1980 S. D. McCurry, G. M. Whitesides, Practical Enzymatic Syntheses of Ribulose 1,5-Bisphosphate and Ribose 5-Phosphate, J Am Chem Soc, vol. 102, 7938-7939, 1980
1980 P. Y. Chang, C. J. Chen, T. M. Lin*, Epidemiologic characteristics of hemorrhoids, Chinese Med J, vol. 27, 498-505, 1980
1979 Resolution of Rs-Mandelic Acid, J Chin Chem Soc, vol. 26, 75-78, 1979
1979 S. T. Chen, K. T. Wang, Enzymic synthesis of opioid peptides, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 576, 247-249, 1979
1979 S. H. Chou, S. T. Chen, K. T. Wang, Enzymatic-Synthesis of Oligopeptide .2. Synthesis of Bis-(N-Protected Amino-Acid) Hydrazides by Papain, J Chin Chem Soc, vol. 26, 11-15, 1979
1979 T. M. Lin*, C. S. Yang, S. M. Tu, C. J. Chen, K. C. Kuo, T. Hirayama, Interaction of factors associated with cancer of the nasopharynx, Cancer, vol. 44, 1419-1423, 1979
1978 S. W. Chen, C. L. Ho, K. T. Wang, Synthesis of cobra neurotoxin, Proc Natl Sci Council ROC, vol. 2, 149-153, 1978
1978 S. T. Chen, C. L. Ho, K. T. Wang, Synthesis of a fully active snake venom cardiotoxin by fragment condensation on solid polymer, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 536, 376-389, 1978
1978 Y. H. Chen, M. C. Hung, K. T. Wang, C. L. Ho, T. B. Lo, Renaturation of a reduced Taiwan cobra cardiotoxin, BIOCHIMICA ET BIOPHYSICA ACTA, vol. 533, 105-111, 1978
1978 C. L. Ho, K. T. Wang, Purfication of synthetic cardiotoxin by affinity chromatography, JOURNAL OF CHROMATOGRAPHY, vol. 154, 13-23, 1978
1978 M. F. Ho, K. T. Wang, Preparation of Optically Pure N-Tert-Butyloxycarbonyl-O-Benzyl-L-Serine and Its Antipode, J Org Chem, vol. 43, 3604-3604, 1978
1978 K. T. Wang, Mutual Resolution of Dl-Ephedrine and N-Benzyloxycarbonyl-Dl-Amino Acids, J Chin Chem Soc, vol. 25, 209-214, 1978
1978 K. T. Wang, Mutual resolution of (+/-)-ephedrine and Z-DL-amino acid induced by seeding chiral salt, Tetrahedron Lett, vol. 19, 3813-3816, 1978
1978 S. H. Chou, S. T. Chen, K. T. Wang, Enzymatic-Synthesis of Oligopeptide .1. Papain-Catalyzed Synthesis of Dipeptide, Tripeptide and Tetrapeptide, J Chin Chem Soc, vol. 25, 215-218, 1978
1978 K. T. Wang, Electrochemistry in Organic-Synthesis .1. Large-Scale Preparation of Cysteine from Cystine, J Chin Chem Soc, vol. 25, 149-151, 1978
1977 S. T. Chen, K. T. Wang, Resolution of Amino-Acids by Enzymes .1. Proteolytic-Enzyme Bromelain for Hydrolysis of L-Amino-Acid Methyl-Esters, J Chin Chem Soc, vol. 24, 129-133, 1977
1976 F. T. Kong, T. C. Lin, K. T. Wang, Synthesis of Taiwan Cobra Venom Cardiotoxin .2. Synthesis of Protected Hexapeptide, Sequence 44-49 and Protected Tripeptide, Sequence 50-52, J Chin Chem Soc, vol. 23, 155-164, 1976